Leptin in Immunology

Leptin in Immunology 1

Leptin in immunology.

Leptin is an adipokine which conveys information on energy availability. In humans, leptin influences energy homeostasis and regulates neuroendocrine function primarily in states of energy deficiency. As a cytokine, leptin also affects thymic homeostasis and, similar to other proinflammatory cytokines, leptin promotes Th1 cell differentiation and cytokine production. We review herein recent adv...

Role of leptin in immunology.

Leptin seems to play an important role in the generation and maintenance of immune responses. Leptin is a cytokine similar in structure to interleukin 2, an important T-cell growth factor. Energy balance and supply is increasingly being realised as an important factor in the survival and function of immune cells. Immune responses are intrinsically energy expensive and come at a cost to the resp...

Immunology

Immunology.

The pathological changes involved in the immunological lung diseases of the bronchiolar region are reviewed. Next, the possibility that BOOP and DPB, two diseases whose causes are presently unknown, are caused by immune responses, is discussed.